We specialize in manufacturing Finerenone with the highest technology and stable quality control , welcome to inquiry it .

General description:
Product Name : Finerenone
CAS No.: 1050477-31-0
[Molecular Formula]: C21H22N4O3
[Molecular Weight]: 378.42
Structure Formula:1050477-31-0

Synonyms:
Finerenone;BAY 94-8862;Finerone;(4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide;BAY948862;Fenaridone;Mr Neri ketone;Finerenone Inn;Finerenone API;Finerenone In-House

Specification:
Appearance:       Off-white solid
Assay:                   Not less than 99.0%
Boiling point:     554.7±50.0 °C
Density:              1.29±0.1 g/cm3
Solubility (25°C): DMSO ≥ 90 mg/mL

Applications:
Finerenone is a novel mineralocorticoid receptor antagonist that has the effect of delaying the progression of chronic kidney disease. Some people may be aware of two other mineralocorticoid receptor antagonists: the diuretic antihypertensive drug spironolactone, and eplerenone.Finerenone is their cognate derivative and is a third-generation mineralocorticoid receptor antagonist. So far, finerenone is the only nonsteroidal mineralocorticoid receptor antagonist to be FDA approved. Finerenone was granted FDA approval on 9 July 2021, followed by the EMA approval on 11 March 2022.

Uses
Finerenone is the first non-steroidal selective mineralocorticoid receptor antagonist, which can be used for the treatment of diabetic nephropathy, chronic kidney disease and end-stage renal disease. It can reduce the proteinuria of patients and improve the glomerular filtration rate.

Biological Activity
Finerenone (FIN, BAY 94-8862) is a highly selective, orally active, nonsteroidal antagonist of mineralocorticoid receptor (MR) with IC50 of 18 nM. Finerenone has the potential to study cardio-renal diseases such as type 2 diabetes and chronic kidney disease.

Important information:
Production capacity: A bulk quantity per months
Delivery : Shipment by Air or Sea
Stock: in stock
Shelf Life: 24 months from manufacture date

Packing:
In plastic bag or fibre drum packing

Please contact us by e-mail sales@haihengpharma.com for quotation requests. Please provide quantity, purity, and any other specific requirements.

Custom SynthesisCustom Synthesis for APIs
We specialize in manufacturing Finerenone with the highest technology and stable quality control , welcome to inquiry it . General description: Product Name : Finerenone CAS No.: 1050477-31-0 : C21H22N4O3 : 378.42 Structure Formula: Synonyms: Finerenone;BAY 94-8862;Finerone;(4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide;BAY948862;Fenaridone;Mr Neri ketone;Finerenone Inn;Finerenone API;Finerenone In-House Specification: Appearance:       Off-white solid Assay:                   Not...