CAS No.: 82956-11-4

We specialize in manufacturing Nafamostat mesylate with the highest technology and stable quality control , our factory has sophisticated technology production route to produce this product ,welcome to inquiry it .

General description:
Product Name : Nafamostat mesylate
CAS No.: 82956-11-4
[Molecular Formula]: C₁₉H₁₇N₅O₂^.2(CH₄O₃S);C₂₁H₂₅N₅O₈S₂
[Molecular Weight]: 539.58
Structure Formula:

Synonyms:
Benzoic acid, 4-((aminoiminomethyl)amino)-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate;Ronastat;Nafamostat mesylate (USAN);Nafamostat dimethanesulfonate;Nafamostat mesilate;Benzoic acid,4-[(aminoiminomethyl)amino]-,6- (aminoiminomethyl)-2-naphthalenyl ester,dimethanesulfonate;FUT 175;Futhan;[N-[4-[6-(azaniumylcarbonimidoyl)naphthalen-2-yl]oxycarbonylphenyl]carbamimidoyl]azanium; methanesulfonate;Nafamostat mesilate (JAN);Nafamostat mesylate [USAN];Ronastat (TN);Nafamostat Mesilate(CAS No: 82956-11-4);6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate;

Specification:
Appearance:         white to beige solid
Assay by (HPLC): Not less than 99.0%
Melting Point: 259-261 °C
Boiling Point: 637.2 °C at 760 mmHg
Flash Point:339.1 °C
Solubility:Soluble in Water (up to 25 mg/ml).
Vapor Pressure: 3.9E-16mmHg at 25°C

Applications:
Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant.Target: Serine ProteaseTranilast (FUT-175) is an antiallergic drug for bronchial asthma. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. It has also been investigated for use as an antiproliferative drug on drug-eluting stents.A 20-40 mg/h dose of FUT-175 prolonged coagulation time sufficiently in the instrumental blood of the extracorporeal circuit but not in the systemic blood. Its anticoagulant activity decreased immediately after hemodialysis. Therefore, we could manage all patients without any bleeding trouble during hemodialysis with FUT-175 as an anticoagulant. Although there were side effects of FUT-175, such as nausea, vomiting, itching and eruption, they were not serious, and FUT-175 could be administered without interruption. FUT-175 seems to be useful as an anticoagulant during hemodialysis for patients susceptible to bleeding.

Important information:
Production capacity per year: on bulk quantity
Delivery : Shipment by Air or Sea
Shelf Life: 24 months from manufacture date

Packing:
In net weight 25kg plastic drum

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