What is Salidroside ?

Salidroside is a natural compound that belongs to the group of compounds known as sesquiterpene lactones. It has been shown to have biological properties in vitro, such as apoptosis induction, autophagy inhibition, and control of cell transformation. Salidroside has also been shown to inhibit skin tumor formation in vivo and to reduce the expression of pro-apoptotic proteins.

The apoptosis pathway is a major target for Salidroside because it may be involved in the regulation of DNA damage responses. Salidroside has been shown to induce apoptosis by inhibiting dinucleotide phosphate (DNP) synthase and activating caspases. This activation is mediated by the protein kinase C (PKC), which leads to activation of caspase-3, poly(ADP-ribose) polymerase, and other pro-apoptotic proteins. Salidroside also induces apoptosis through a pathway involving mitochondria and Bcl.

Salidroside (Sal), also known as rhodioloside, is a glycoside compound and an active ingredient that can be found in Rhodiola rosea (R. rosea) and other species of Rhodiola. R. Rosea, also known as golden root, is a perennial plant that is native to the Arctic regions of Europe, Asia, and America and has been traditionally used for centuries to treat a wide range of ailments, including fatigue, depression, and anxiety.

Salidroside was first isolated and identified in R. rosea in the 1960s and has since been the subject of numerous scientific studies due to its potential therapeutic properties.

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